Nuclear Magnetic Resonance (NMR) Spectroscopy is used intensively along with otherancillary spectroscopic and characterization techniques. The design and implementation ofHigh Throughput NMR Spectroscopy is a key challenge to accelerate the drug discoveryprocess. On the other hand, the current conventional NMR technologies are expensive andbulky. The development of novel handheld NMR spectroscopy is a key challenge towardsNMR spectroscopy for Point-of-Care (PoC) diagnostics applications.

This thesis addresses the above-mentioned challenges of High Throughput NMRSpectroscopy and Handheld NMR spectroscopy by developing new integrated circuitsdedicated to NMR spectroscopy using Complementary Metal Oxide Semiconductor(CMOS) technology. Simulation and characterization results were also used to prove thefunctionality and applicability of the proposed techniques. We have designed two CMOSchips using 0.13-μm technology, first chip includes number of new vertical microcoils andLNA with 780 pV/√Hz at 300 MHz and the second one is a new dual-path NMR receiver.