本文介绍了基于 Windows CE 的PC104 模块与基于MCS51 单片机的GPIB 接口构成自动测试仪器的实现方法，其中GPIB 接口与单片机间的数据传输和PC104 模块与单片机之间的串行通信是系统实现的关键。本文详细介绍了整个系统的软件与硬件设计。关键词：GPIB 接口；PC104；Windows CE；串行通信；多线程Abstract: This paper described the implementation of Auto-Measuring Instruments making up of PC104 module based on Windows CE and GPIB interface based on MCS51 Microcontroller.Data transmission between GPIB bus and Microcontroller and serial communication between PC104 and Microcontroller are the vital parts of the measurement system. It is explicated how to connect the hardware and design the software.Keywords: GPIB(General Purpose Interface Bus); PC104; Windows CE; Serialcommunication; Multi-thread